The new comedy-drama 50/50 centers around a cancerous presence, and that refers to Seth Rogen as much as it does to the malignant tumor found located on the spine of young Adam (Joseph Gordon-Levitt). Carve Rogen out of the picture, and its chances of being a truly moving film about people coping in sickness and in health increase exponentially.
This is nothing personal about Rogen, who I generally enjoy watching — heck, I didn't even mind him bringing his slobbery man-boy act to the iconic role of the Green Hornet. But 50/50, inspired by scripter Will Reiser's own battle with cancer, doesn't need his services, which only get in the way of a potentially heart-rending story about how a 20-something who theoretically has his whole life ahead of him must cope with a tragedy that threatens to cheat him out of his future. Gordon-Levitt delivers a sensitive portrayal as Adam, perpetually trying to get a grasp on emotions that understandably don't know where to go. Adam shares an interesting relationship with his therapist (Up in the Air Oscar nominee Anna Kendrick), a medical newbie who isn't quite certain how to comfort her patient. He has trouble with his girlfriend (Bryce Dallas Howard), who's mentally ill-equipped to deal with a partner who's now bald and barfing all over the place. He bonds with two older cancer patients (Matt Frewer and national treasure Philip Baker Hall) who take him under their wing. And he has difficulties communicating with his mother (Anjelica Huston), a drama queen who's already dealing with an Alzheimer's-afflicted husband (Serge Houde).
These are all intriguing relationships, but every time we become immersed in these particular character dynamics, along comes Rogen as Adam's unlikely best friend Kyle. Kyle clearly has Adam's back, and had Rogen, in his capacity as one of the film's producers, graciously allowed another actor to play the role, we might have had something special. But the film's delicate mood is broken anytime Kyle opens his mouth to talk about shaving his balls or getting laid or basically anything that trumpets his obnoxiousness. 50/50 is a good movie about 60% of the time, but a higher percentage would have been appreciated.